Restless Leg Syndrome
(RLS)

RLS is a sleep disorder in which people have creeping or crawling sensations in their legs when they sit or lie down in order to sleep and there is an irresistible urge to move their legs. These sensations go away when the person gets up and walks around. The sensations can cause discomfort and make it difficult to fall asleep. Many people with this disorder spend their evenings and nights pacing the floor. RLS can be due to a central nervous system disorder, or may be associated with other medical conditions such as kidney disease, poor circulation in the legs, alcoholism, neuropathy, vitamin or mineral deficiencies. Certain medications, caffeine, smoking, etc. can also aggravate RLS. RLS occurs in both sexes and although it is often diagnosed in older people, the symptoms can begin at any time. There is no laboratory test that can confirm a diagnosis of RLS. However, basic lab tests may be done to rule out anemia (iron deficiency) that may be associated with RLS. Diagnosis of RLS is most often made on the basis of a medical history. People with RLS may complain of insomnia, difficulty sleeping, or daytime fatigue and sleepiness.

Periodic Limb Movement Disorder
(PLMD)

Most people with RLS will have PLMD. People with PLMD are often not aware of these movements and it is usually the bed partner who complains about the person's leg kicking or jerking in sleep. PLMD typically occurs 20 to 40 seconds apart, on and off during the night. Some people may have hundreds of leg jerking movements each night that can lead to frequent arousals and disrupted sleep. People with PLMD may experience trouble falling asleep and staying asleep, and may feel daytime fatigue and/or sleepiness. Due to chronic sleep deprivation and daytime sleepiness, people may have problems with jobs, social life, and personal relationships (due to mood swings). An overnight sleep study may be required to determine whether PLMD or other sleep-related physiological disturbances are present.



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